广东工业大学环境科学与工程学院教授，硕导

一 基本信息

李桂英，博士、特聘教授，广东省特支计划百千万领军人才。长期从事光催化杀菌机理，病原微生物耐药性形成机制、健康效应与控制，有机污染物环境健康效应，毒害有机物的生物降解的应用基础与研发工作。发表SCI论文290余篇，包括入选ESI高被引10篇和热点2篇，基础成果受到国内外同行广泛关注，SCI引用11000余次，成果入编中科院发展战略光化学专著和英文专著章节。任SCI期刊Int J Environ Res Public Health、Res J Biotech编委和2个SCI期刊客座主编。申请专利50件，授权36件(美国发明专利1件)。现主持NSFC-广东联合基金重点和国基面上各1项，完成国基面上3项及省部级重点10余项。广东省本土创新团队、省基金团队和教育厅团队核心成员。获环境保护科学技术奖一等奖、国家教育部自然科学奖二等奖、广东省自然科学奖一等奖。

二 研究方向

病原微生物耐药性形成机制、健康效应与控制、有机污染物环境健康效应、生物降解有机污染物的基础与应用研究。

三 教育经历

2006.07－2010.05  澳大利亚Griffith Univeristy，博士学位

1999.09－2002.07  西北师范大学，硕士学位

1992.09－1996.07  南京农业大学，学士学位

四 工作经历

2015.11- 今   广东工业大学 环境科学与工程学院和环境健康与污染控制研究中心，教授

2009.09—2015.10   中科院广州地球化学研究所，副研究员

2002.07—2009.08   中科院广州地球化学研究所，助理研究员

1996.07—1999.07   西北师范大学生命科学学院，研究实习员

五 学术兼职

1.Int. J. Environ. Res. Public Health   (SCI收录)国际期刊编委；

2.Res. J. Biotechnol.(SCI收录)国际期刊编委；

3.Ecotoxicol. Environ. Saf. (SCI收录)客座编辑；

4.Environ. Geochem. Health (SCI收录)客座编辑。

六 主要荣誉

2020年 环境保护科学技术奖一等奖(第二完成人）

2016年 广东省特支计划百千万工程领军人才

2015年 国家教育部自然科学奖二等奖(第三完成人）

七 科研情况

目前主持/完成国家自然基金面上项目共3项，广东省科技计划重点项目2项，中国科学院支撑服务国家战略性新兴产业科技行动计划专项项目1项，瑞典国际科学基金项目1项和广东省自然科学基金2项。 担任Res. J. Biotechnol.(SCI收录)国际期刊编委。 已发表包括包括J. catal.、Environ. Sci. Technol.、Water Res.、Appl Catal B等环境领域高档次的SCI论文100余篇，所有论文累计引用次数1800多次，H-index维25。申请相关专利36件，授权28件，其中包括授权美国发明专利1件。

八 科研项目

1) 国家自然科学基金联合基金项目 (U1901210 ), 2020.01－2023.12, 生活垃圾发酵形成耐药菌及其生物气溶胶的演化机制与呼吸健康效应，主持

2）国家自然科学基金面上项目 (41877363), 2019.01－2022.12, 生活垃圾腐烂释放含硫有机废气与细菌群落的相互作用机制及其细胞毒性效应研究, 主持

3）国家自然科学基金 (41573086)，2016.01－2019.12，典型耐药菌及耐药基因在光和矿物作用下的环境地球化学转化机制研究

4) 国家自然科学基金 (41373103)，2014.01－2017.12，典型溴代酚类阻燃剂的环境行为及其微生物强化降解机制研究

5) 国家自然科学基金 (21077104)，2011.01－2013.12，基于原位生成杀菌剂的光电催化方法及机理研究

6) 国家基金联合基金(U1201234)子课题，2013.01－2016.12，复合污染流域水体与沉积物中毒性污染物的归趋与修复－以北江和龙江为例

7) 中国科学院支撑服务国家战略性新兴产业科技行动计划专项项目(ZNGZ-2012-002)，2012.01－2014.12，两级顺序式生物反应器处理恶臭有机废气新技术研发与应用

8) 广东省科技计划重点项目(2012A030600004), 2012.10－2015.09, 高效生物新技术净化生活垃圾恶臭废气的研发及应用示范

九 科研成果

1) Guiying Li, Xiaofang Chen, Hongliang Yin, Wanjun Wang, Po Keung Wong, Taicheng An⁎. Natural sphalerite nanoparticles can accelerate horizontal transfer of plasmid-mediated antibiotic-resistance genes. Environ. Int. 2020, 136, 105497.

2) Hao Ji, Yiwei Cai, Zaixia Wang, Guiying Li*, Taicheng An. Sub-lethal photocatalysis promotes horizontal transfer of antibiotic resistance genes by conjugation and transformability. Water Res. 2022, 221, 118808.

3) Xiaofang Chen, Hongliang Yin, Guiying Li*, Wanjun Wang, Po Keung Wong, Huijun Zhao, Taicheng An*. Antibiotic-resistance gene transfer in antibiotic-resistance bacteria under different light irradiation: Implications from oxidative stress and gene expression. Water Res. 2019, 149, 282-291.

4) Guiying Li, Xiaolu Liu, Taicheng An*, PoKeung  Wong, Huijun Zhao*. A nov el method developed for estimating mineralization efficiencies and its application in PC and PEC degradations of large molecule biological compounds with unknown chemical formula. Water Res. 2016, 95, 150-158.

5) Guiying Li, Xin Nie, Jiangyao Chen, PoKeung  Wong, Taicheng An*, Hiromi Yamashita, Huijun Zhao*. Enhanced simultaneous PEC eradication of bacteria and antibiotics by facilely fabricated high-activity {001} facets TiO2 mounted onto TiO2 nanotubular photoanode. Water Res. 2016, 101: 597-605.

6) Guiying Li, Xin Nie, Jiangyao Chen, Qi Jiang, Taicheng An*, Haimin Zhang, PoKeung Wong, Huijun Zhao*. Enhanced visible-light-driven photocatalytic inactivation of E. coli using g-C3N4/TiO2 hybrid photocatalyst synthesized using a hydrothermal-calcination approach. Water Res. 2015, 86: 17-24.

7) Guiying Li,  Xin Nie, Qi Jiang, Taicheng An*. Can environmental pharmaceuticals be photocatalytically degraded and completely mineralized in water using g-C3N4/TiO2 under visible light irradiation-Implications of persistent toxic intermediates, Appl. Catal. B: Environ. 2016, 180: 726-732.

8) Guiying Li, Xiaolu Liu, Haimin Zhang, PoKeung Wong, Taicheng An*, Huijun Zhao*. Comparative studies of photocatalytic and photoelectrocatalytic inactivation of E. coli in presence of halides. Appl. Catal. B: Environ. 2013, 140-141: 225-232.

9) Yiwei Cai, Tong Sun, Guiying Li*, Taicheng An. Traditional and Emerging Water Disinfection Technologies Challenging the Control of Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes. ACS ES&T Eng. 2021, 1(7), 1046-1064.

10) Zhishu Liang, Wen Liao, Yun Yu, Guiying Li*, Taicheng An. How Does Vegetable Waste Decomposition Influence the Antibiotic Resistome and the Human Bacterial Pathogen Structure in Leachates? ACS ES&T Water 2022, 2(1), 226-236.

11) Guiying Li, Yi Liao, Junjie Hu, Lirong Lu, Yanan Zhang, Bing Li, Taicheng An*. Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure. Environ. Pollut. 2019, 252: 1216-1224.

12) Yanan Zhang, Pu Mao, Guiying Li*,  Junjie Hu, Yingxin Yu, Taicheng An. Delineation of 3D dose-time-toxicity in human pulmonary epithelial Beas-2B cells induced by decabromodiphenyl ether (BDE209). Environ. Pollut. 2018, 243: 661-669.

13)  Guiying Li, Jukun Xiong, Taicheng An*, PoKeung Wong.  Enhancing tetrabromobisphenolA biodegradation in river sediment microcosms and understanding the corresponding microbial community. Environ. Pollut. 2016, 208: 796-802.

14) Yuna Zhang, Zhishu Liang, Changcheng Tang,Wen Liao,Yun Yu, Guiying Li*, Yan Yang, Taicheng An. Malodorous gases production from food wastes decomposition by indigenous microorganisms. Sci. Total Environ. 2020, 717, 137175.

15)Zhishu Liang, Guiying Li*, Bixian Mai, Taicheng An. Biodegradation of typical BFRs 2,4,6-tribromophenol by an indigenous strain Bacillus sp. GZT isolated from e-waste dismantling area through functional heterologous expression. Sci. Total Environ. 2019, 697, 134159.

16)  Ranjit Das, Guiying Li*,  Bixian Mai, Taicheng An. Spore cells from BPA degrading bacteria Bacillus sp. GZB displaying high laccase activity and stability for BPA degradation. Sci. Total Environ. 2018, 640-641: 798-806.

17)  Jukun Xiong, Guiying Li*,  Taicheng An*. The microbial degradation of 2,4,6-tribromophenol (TBP) in water/sediments interface: Investigating bioaugmentation using Bacillus sp. GZT. Sci. Total Environ. 2017, 575: 573-580.

18) Yi Yang, Hao Luo, Ranran Liu, Guiying Li*, Yingxin Yu*, Taicheng An. The exposure risk of typical VOCs to the human beings via inhalation based on the respiratory deposition rates by proton transfer reaction-time of flight-mass spectrometer. Ecotoxicol. Environ. Saf. 2020, 197, 110615.

19)Guiying Li, Huan Yang, Taicheng An*, Yujuan Lu*. Antibiotics elimination and risk reduction at two drinking water treatment plants by using different conventional treatment techniques. Ecotoxicol. Environ. Saf. 2018, 158: 154-161.

20)Zhishu Liang, Jijun Wang, Yuna Zhang, Cheng Han, Shengtao Ma, Jiangyao Chen, Guiying Li*, Taicheng An. Removal of volatile organic compounds (VOCs) emitted from a textile dyeing wastewater treatment plant and the attenuation of respiratory health risks using a pilot-scale biofilter. J. Clean. Prod. 2020, 253, 120019.

21) Guiying Li, Xiaolu Liu, Haimin Zhang, PoKeung Wong, Taicheng An*, Wenqu Zhou, Bing Li, Huijun Zhao*. Adenovirus inactivation by in-situ photocatalytically and photoelectrocatalytically generated halogen viricides. Chem. Eng. J. 2014, 253: 538-543.

22)  Guiying Li,  Hongwei Sun, Zhengyong Zhang, Taicheng An*,  Jianfang Hu. Distribution profile, health risk and elimination of model  atmospheric SVOCs associated with a typical municipal garbage  compressing station in Guangzhou, South China. Atmos. Environ. 2013, 76:173-180.

23) Zhishu Liang, Yuna Zhang, Tao He, Yun Yu, Wen Liao, Guiying Li*, Taicheng An. The formation mechanism of antibiotic-resistance genes associated with bacterial communities during biological decomposition of household garbage. J. Hazard. Mater. 2020, 398, 122973.

24) Guiying Li, Zhengyong Zhang, Hongwei Sun, Jiangyao Chen, Taicheng An*, Bing Li. Pollution profiles, health risk of VOCs and biohazards emitted from municipal solid waste transfer station and elimination by an integrated biological-photocatalytic flow system: A pilot-scale investigation, J. Hazard. Mater. 2013, 250-251: 147-154.

25) Ranjit Das, Zhishu Liang, Guiying Li*, Taicheng An. A non-blue laccase of Bacillus sp. GZB displays manganese-oxidase activity: A study of laccase characterization, Mn(II) oxidation and prediction of Mn(II) oxidation mechanism. Chemosphere 2020, 252, 126619.

26)Zhishu Liang, Guiying Li*, Bixian Mai, Huimin Ma, Taicheng An. Application of a novel gene encoding bromophenol dehalogenase from Ochrobactrum sp. T in TBBPA degradation. Chemosphere 2019, 217, 507-515.

27) Zhishu Liang, Guiying Li*, Jukun Xiong, Bixian Mai, Taicheng An. Purification, molecular characterization and metabolic mechanism of an aerobic tetrabromobisphenol A dehalogenase, a key enzyme of halorespiration in Ochrobactrum sp. T. Chemosphere 2019, 237, 124461.

28)  Jukun Xiong, Taicheng An, Guiying Li*,  Pingan Peng. Accelerated biodegradation of BPA in water-sediment microcosms with Bacillus sp. GZB and the associated bacterial community structure. Chemosphere 2017, 184:120-126.

29) Yingjun Wu, Guiying Li∗, Yan Yang, Taicheng An. Pollution evaluation and health risk assessment of airborne toxic metals in both indoors and outdoors of the Pearl River Delta, China. Environ. Res. 2019, 179, 108793.

30)  Guiying Li, Xiaolu Liu, Haimin Zhang, Taicheng An*, Shanqing Zhang, Anthony R Carroll, Huijun Zhao*. In situ photoelectrocatalytic generation of bactericide for instant inactivation and rapid decomposition of Gram-negative bacteria. J. Catal. 2011, 277(1): 88-94.   

十  联系方式

E-mail：ligy1999@163.com;

通讯地址：广州大学城外环西路100号 环境科学与工程学院

课题团队网站：http:// www.antaicheng-group.cn